COVID-19 Testing
COVID-19 Testing

COVID-19 Testing Solutions

To help address and fight the global pandemic caused by SARS-COV-2 since late 2019, Quantabio provides three essential RT-qPCR ToughTM master mixes to help research labs and testing providers eliminate extraction and purification while overcoming common PCR inhibitors to accurately detect COVID-19 at low limits of detection (LOD). 

Our RT-qPCR master mixes being used for COVID-19 in these latest developments

COVID 19 map

Reagents Manufactured for
+ 100 Million Tests

Quantabio proudly supports and partners with thousands of Testing labs in more than 37 countries around the world.

Workflow Solutions

Dried blood spots

Clinical/ Environmental sample

DNA Extraction

RNA Extraction



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Determine which product is right for you.


qScript XLT 1-Step RT-qPCR ToughMix qScript 1-Step Virus ToughMix UltraPlex 1-Step ToughMix
Recommended in CDC protocol x x
Detection purified RNA x x x
Extraction-free detection x x
Saliva-direct detection x
Formulation 2X master mix 2X master mix 4X master mix
Taq Hot Start Yes Yes Yes
RT Hot Start No Yes Yes
Chemistry 1 tube SuperMix 1 tube SuperMix 1 tube SuperMix
Performance ++++ ++++ ++++
Cycling Conditions Fast or Standard qPCR Cycling Fast or Standard qPCR Cycling Fast or Standard qPCR Cycling
Multiplex Capabilty Up to 4 targets Up to 4 targets Up to 5 targets
Sensitivity +++ ++++ ++++
Inhibitor Tolerance Yes Yes Yes
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Customer Testimonials
UltraPlex 1-Step ToughMix

"Compared to other 1-step qRT-PCR mixes we have used, UltraPlex 1-Step ToughMix (4X) Low-ROX, 500R performs with the same sensitivity when testing using SARS-CoV-2-spiked saliva samples, but is easier to use and at a significantly lower price per reaction. The mix requires little to no time to thaw, decreasing the time required when preparing samples. The mix is also conveniently aliquoted into multiple tubes, reducing the chance for contamination as opposed to a single, high volume aliquot. Overall, these factors make this a better overall product as compared to competing companies (e.g., Thermo Fisher Scientific or Zymo) and we will continue to use this moving forward."

Rhoel R. D., PhD, MPH Professor of Infectious Diseases UF Eminent Scholar Director | CDC Southeastern Regional Center of Excellence for Vector Borne Diseases
qScript 1-Step Virus ToughMix

"1-Step Virus ToughMix performed BETTER than other 3 mixes and amplified very well the S target from SARS-CoV-2 in a highly multiplex environment."

Guillermo C. | Project Coordinator Sick Kids Molecular Diagnostics Lab
News and Publications

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Starting Template

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Detection Chemistry

Multiplexing (more than 3 targets)

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  • Applied Biosystems 7500
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  • Stratagene Mx3000P®
  • Stratagene Mx3005P™
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  • BioRad iCycler iQ™
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  • BioRad iQ™5

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