Precision Reagents for Modern Pathogen Detection Laboratories
As public health laboratories and clinical research labs expand molecular testing for infectious diseases, the demand for sensitive, resilient assays with faster turnaround times continues to grow. Scientists require solutions that deliver confident detection across diverse sample types while maintaining performance in high‑throughput and resource‑limited settings.
Quantabio addresses these challenges with qPCR, RT‑qPCR, and next‑generation sequencing (NGS) solutions designed to maintain assay sensitivity and consistency across inhibitor‑rich samples. Our technologies support reliable low limits of detection for viral, bacterial, and fungal pathogens—helping laboratories generate dependable results when they matter most.
Check out a list of validated PHL assay using Quantabio reagents
5 Reasons Why Pathogen Detection Matters
- Protects Population Health Through Early Detection
Rapid and accurate pathogen detection enables earlier diagnosis, treatment, and intervention to help reduce disease transmission.
Sensitive molecular testing can identify infections before they spread widely through communities. - Enables Rapid Outbreak Containment and Surveillance
Scalable testing solutions support real-time monitoring of infectious diseases, helping laboratories and public health agencies quickly identify outbreaks and track emerging threats. - Guides Clinical & Public Health Decision Making
Accurate pathogen identification helps clinicians select appropriate treatments while providing data that informs public health policies, vaccination strategies, and resource planning. - Strengthens Preparedness for Emerging Threats
Flexible molecular testing technologies enable rapid development and deployment of assays for new pathogens, improving readiness for future outbreaks and public health emergencies. - Safeguards Economic & Social Stability
Early pathogen detection helps minimize disruptions to healthcare systems, workplaces, education, and travel by supporting faster intervention and reducing widespread transmission.
Key Applications
Bacterial & Fungal Detection
qPCR
Rapid and accurate detection and quantification of bacterial and fungal DNA by qPCR is critical for identifying species and supporting informed triage of infectious pathogens. Quantabio qPCR solutions deliver robust amplification from inhibitor‑rich samples to support confident detection and quantification.
Multiplex Virus Detection
RT‑qPCR
Increase results per sample with easy‑to‑use, one‑step RT‑qPCR workflows supporting up to five multiplex RNA targets. These solutions enable detection and differentiation of multiple respiratory and other RNA viruses—including SARS‑CoV‑2, influenza A/B, RSV, and more — in a single reaction.
Surveillance & Genotyping
Sequencing
Metagenomic sequencing using short‑ and long‑read NGS enables broad identification of infectious pathogens, detection of co‑infections, and monitoring of emerging or re‑emerging strains. Quantabio sequencing workflows support population‑level surveillance and genotyping through reliable library preparation and amplification of complex targets.
Overcoming Molecular Testing Challenges
Clinical and environmental samples — including swabs, blood, saliva, stool, and environmental surfaces — often contain PCR inhibitors that can compromise amplification efficiency and data quality. These challenges can delay results and hinder public health decision‑making.
Quantabio’s proprietary ToughMix® chemistry powers through common inhibitors to deliver reliable amplification from challenging samples. ToughMix formulations enable sensitive detection even from crude lysates, supporting extraction‑free workflows that reduce cost, time, and complexity — particularly valuable in resource‑limited or high‑throughput testing environments.
| Inhibitors | Common Source | Reagent Performance | |
| Competitor | ToughMix | ||
| Polyphenols | Plant extracts | – | |
| Humic acid | Soil Plant tissues |
– | |
| Hematin | Dried bloods Blood spots |
– | |
| Hemoglobin | Blood | ||
| Polysaccharides | Feces Plant tissues |
– | |
| Melanin | Hair Skin |
– | |
ToughMix
Designed for Diverse Pathogen qPCR Applications
Inhibitor-tolerant qPCR detection and quantification enables faster time to result and can reduce the need for laborious extraction methods in resource-limited settings.
qPCR Workflow
sparQ
Designed for Diverse Pathogen Sequencing
Next-generation sequencing is a powerful tool for the surveillance of new and evolving pathogens. In particular, metagenomic sequencing can be used to identify co-infections or novel divergent viruses that may be missed by lower throughput methods like qPCR analysis.
Quantabio’s sparQ library prep kits deliver a rapid, robust, and cost-effective solution for NGS library generation to support pathogen sequencing workflows.
Whole Genome Sequencing Workflow
Size Selection
Discover the Right Solution for Your Application
From inhibitor‑tolerant qPCR and RT‑qPCR to advanced sequencing workflows, Quantabio provides trusted solutions for pathogen detection, surveillance, and genotyping.
qPCR Applications
| Product |
Bacterial / Fungal Pathogen Detection / Quantification |
Viral Pathogen Detection / Quantification |
Genotyping |
|---|---|---|---|
| PerfeCTa qPCR ToughMix / Multiplex ToughMix | X | X | |
| UltraPlex 1‑Step ToughMix | X | X | |
| qScript XLT 1‑Step ToughMix | X | X | |
| eQo 1‑Step ToughMix | X | X | |
| qScript Ultra Flex Kit | X |
Sequencing Applications
| Product |
16S / 18S / ITS Amplicon Sequencing |
AMR Testing and Tracking |
Whole Genome Sequencing |
Whole Viral RNA Sequencing |
Long Read Sequencing |
|---|---|---|---|---|---|
| qScript Ultra Flex Kit | X | X | |||
| repliQa HiFi ToughMix | X | X | X | X | |
| sparQ DNA Library Prep Kits | X | X | X |
Validated Pathogen Detection Assays in Public Health
Quantabio is committed to supporting pathogen detection utilizing molecular tests for public health applications with our ToughMix PCR, qPCR and RT-qPCR reagents as well as NGS solutions. Since 2013, Quantabio products have been cited in testing protocols for viruses such as H7N9 Avian Influenza, Polio and COVID-19 and bacteria such as Legionella spp., Mycoplasma pneumoniae and Shiga toxin producing E. coli. These protocols are continually expanded to include new pathogens, or improve previous assays.
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