Our reagents are recommended for newborn screening by key opinion leaders. Extracta DBS in combination with ToughMix chemistry enable simple and cost effective processing of DNA from dried blood spots (DBS) for molecular testing using qPCR.

Quantabio reagents streamline workflows, improve performance and reduce testing costs in Public Health Labs for multiple testing applications

What Customers Say

We make our technology choices based on several criteria, such as ease of use, consistent performance, and applicability to challenging samples. I have tried several alternatives and the combination of Quantabio Extracta DBS and ToughMix® reagent provided the best overall assay performance when we performed real-time PCR assays to measure T cell receptor excision circles (TRECs) used for SCID screening.

Customer Profile Story

Mei Baker, MD, FACMG
Co-Director of Newborn Screening
We used the qScript XLT 1-step RT-qPCR ToughMix to reliably and very quickly identify an experimental drug candidate and demonstrate its efficacy to correct the debilitating effect of an inherited disease. The immediate success and impeccable performance of this mix shortened our labs time to result and confirmation easily by 2-3 months.
Lead Scientist / Researcher
TransLab, Children’s Hospital Boston

SCID & SMA Testing

Featured Posters

A Multiplexed Real-time PCR Assay to Detect SCID and SMN1 Homozygous Exon 7 Deletion, and A Droplet Digital PCR Assay to Assess SMN2 Copy Numbers, in Newborn screening for Spinal Muscular Atrophy

Download Featured Poster

Newborn Screening for Severe Combined Immunodeficiency: An Improved Real‐time PCR Assay

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We offer multiple qPCR and RT-qPCR mastermixes that have been widely used and deployed in the fight against COVID-19 amongst other infectious diseases.


Determine which RT-qPCR kit is right for your research needs and request a sample.

qScript XLT 1-Step RT-qPCR ToughMix UltraPlex 1-Step ToughMix qScript 1-Step Virus ToughMix
CDC Recommendations
Recommended in Protocol
Direct Heat Lysis
Sars-CoV-2 & Flu A/B
Product Features & Benefits
Formulation 2X master mix 4X master mix 2X master mix
Taq Hot Start Yes Yes Yes
RT Hot Start No Yes Yes
Chemistry 1 tube SuperMix 1 tube SuperMix 1 tube SuperMix
Performance ++++ ++++ ++++
Cycling Conditions Fast or Standard qPCR Cycling Fast or Standard qPCR Cycling Fast or Standard qPCR Cycling
Multiplex Capabilty Up to 4 targets Up to 5 targets Up to 4 targets
Sensitivity +++ ++++ ++++
Inhibitor Tolerance Yes Yes Yes

Check out our newest products

repliQa HiFi ToughMix
Superior speed and inhibitor tolerance


AccuStart Long Range SuperMix
Superior sensitivity and multiplexing for DNA amplification of long targets


Doing NGS?
Check out our NGS Workflow Solutions